staff member Beijing Tsinghua Changgung Hospital, Tsinghua University
Disclosure(s):
Jinlan Lin, MD: No financial relationships to disclose
Background: Infection by carbapenem resistant organism (CRO) poses a significant threat to inpatients. This study analyzes the trend of hospital infection/colonization in CRO through target surveillance, optimization of information dissemination, and ward management measures, providing a basis for CRO prevention and control.
Methods: Target surveillance was conducted on inpatients with CRO strains,including carbapenem-resistant Enterobacteriaceae (CRE), Acinetobacter baumannii (CR-AB), and Pseudomonas aeruginosa (CR-PA) in a tertiary teaching hospital from 2016 to 2022.After removing duplicate and contaminated strains, whether the newly detected CRO strains were brought in or acquired within the hospital were determined. The clinical department implemented contact isolation measures, with single room isolation in the ICU and bedside isolation in the general ward. When staff came into contact with patients, they wore isolation clothes, gloves, and masks. The environment was disinfected three times a day, and medical equipment and items were disinfected after each use. Other management measures were divided into three stages. The first stage was from 2016 to 2017, during which infection prevention and control professionals called the doctor-in-charge and nurse-in-charge daily to remind them to implement isolation measures. The second stage was from 2018 to 2019, when the laboratory cultivated CRO strains, the system automatically sent isolation reminders to the doctor-in-charge and nurse-in-charge. The third stage was from 2020 to 2022. Based on the above measures, implementing closed ward management, including refusal to visit, increasing the frequency of overall environmental cleaning and disinfection in the ward, and increased the frequency of training and promotion of various prevention and control measures.
Results: The hospital infection/colonization rates were 4.34 ‰, 4.08 ‰, and 2.74 ‰, respectively.The difference between the latter two was statistically significant(χ²= 21.11, P< 0.01).
Conclusions: Through target surveillance, optimizing the management measures of the ward can effectively reduce the hospital infection/colonization rate of CRO in inpatient wards.
Learning Objectives:
Upon completion, participant will be able to learn CRO target surveillance methods and diagnostic criteria.
Upon completion, participant will be able to master CRO contact isolation measures.
Upon completion, participant will be able to implement special measures to reduce MDRO infection based on local conditions.
